Front Cover: Mustard Carbonate Analogues as Sustainable Reagents for the Aminoalkylation of Phenols (24/2021)
نویسندگان
چکیده
The Front Cover shows the one-pot procedure for introduction of aminoalkyl chain through dialkyl carbonate chemistry into different phenolic substrates. This green approach is a direct alcohol substitution that avoids use chlorine giving CO2 and ethanol as only reaction by-products. proposed has numerous potential applications N,N-dialkyl ethylamine moieties are incorporated in many pharmacophore scaffolds such Tamoxifen, Raloxifene, Amiodarone, Phenyltoloxamine Trifenagrel. authors thank Thomas Bassano creating artwork. More information can be found Communication by F. Aricò et al.
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2021
ISSN: ['1434-193X', '1099-0690']
DOI: https://doi.org/10.1002/ejoc.202100602